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Clinical trial reforms that once seemed radical
How randomized controlled trials, preregistration, and results reporting became standard practice.
9 hrs ago
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Saloni Dattani
6
3
February 2026
AI won't automatically accelerate clinical trials
A response to Dario Amodei.
Feb 28
•
Ruxandra Teslo
14
4
2
Learning from Australia: towards a "Clinic-in-the-loop" future
The Australian framework for early-stage trials has been around for 30 years and shows speed and safety do not have to come at each other's expense
Feb 18
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Ruxandra Teslo
15
4
8
Will Bayesian Statistics Transform Trials?
FDA has finally published its Bayesian guidance. Will it matter?
Feb 16
•
Adam Kroetsch
22
5
6
The FDA should not change its mind last minute
In which Ruxandra explains why the consequences of the FDA's RTF to Moderna extend far beyond the current vaccine program
Feb 11
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Ruxandra Teslo
26
5
9
The case for sharing clinical trial data
The story behind the first statin and how its development was almost derailed, and the implications of sharing clinical trial data.
Feb 10
•
Saloni Dattani
20
6
8
Introducing the Clinical Trials Abundance blog
Ideas, thoughts and commentary about clinical trials and how to make them more efficient by Saloni Dattani, Adam Kroetsch, Manjari Narayan, Ruxandra…
Feb 9
•
Saloni Dattani
,
Adam Kroetsch
,
Ruxandra Teslo
,
Manjari Narayan
, and
Witold Więcek
42
7
10
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